How Long After Giving Tylenol Can You Give Motrin

How Long After Giving Tylenol Can You Give Motrin?

When your child is in pain or has a fever, it’s natural to want to provide them with relief as quickly as possible. Many parents often wonder how long they should wait after giving their child Tylenol before administering Motrin, or vice versa. Here’s what you need to know about these two commonly used medications and their timing.

Tylenol and Motrin are both over-the-counter medications used to reduce pain and fever. Tylenol contains acetaminophen, while Motrin contains ibuprofen. They work differently in the body and can be used together if necessary.

The recommended time interval between Tylenol and Motrin administration is typically about four to six hours. This allows enough time for each medication to take effect and reduces the risk of overdosing or overloading the liver with acetaminophen. However, it’s always best to consult with your child’s pediatrician or pharmacist for personalized advice based on your child’s age, weight, and specific medical condition.


1. Can I give Tylenol and Motrin at the same time?
No, it is not recommended to give both medications simultaneously. They should be spaced out by at least four to six hours.

2. Which medication should I give first?
There is no specific order in which to administer Tylenol and Motrin. As long as the time interval between doses is maintained, either medication can be given first.

3. How often can I alternate between Tylenol and Motrin?
It is generally advised to alternate between Tylenol and Motrin every four to six hours, as needed, within the recommended dosage guidelines.

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4. Can I give Tylenol or Motrin if my child is already taking other medications?
It is important to consult with a healthcare professional or pharmacist to ensure there are no potential drug interactions. They can provide guidance on how to safely administer multiple medications.

5. Can I give Tylenol or Motrin on an empty stomach?
Both medications can be given with or without food. However, if your child experiences stomach discomfort after taking either medication, giving it with food may help.

6. Can I use a generic brand instead of Tylenol or Motrin?
Generic versions of these medications typically contain the same active ingredients and can be safely used. However, it’s important to carefully read the labels and follow the recommended dosage guidelines.

7. What if my child’s symptoms persist despite giving Tylenol and Motrin?
If your child’s symptoms persist or worsen, it is important to consult with a healthcare professional. They can provide further guidance or recommend additional treatment options.

Remember, it’s always best to consult with a healthcare professional for personalized advice regarding medication administration and dosing for your child.